WOLFRAM SYNDROME
About ten years ago a very good friend and Chiropractor was killed an an auto accident, his name was Dr. Jay Penola and he practiced in the Pompton Plains, Riverdale area of New Jersey. I use to cover for him periodically and therefore I was asked if I would be willing to administer his practice besides my own. I administered Dr. Penola's practice for about one and a half years
During the time I was practicing and administering this practice a patient came in with neck pain, and back pain with muscle weakness. In the process of taking a case history he revealed to me that he was diagnosed with Wolfram Syndrome (DIDMOAD). He was American of Greek ancestry, short for his age, early 20's, had Diabetes Insipidus,Diabetes Mellitus, Optic Atropy and some Deafness, he also had weakness of the kidney's and muscular weakness and constant fatigue.
The primary symptoms of Wolfram Syndrome (DIDMOAD) are Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy and Deafness and various other disorders can be associated. This Syndrome affects the brain (especially the brain stem) and the central nervous system. At the time I was taking care of this gentleman he was only one of 167 people in the world that were known to have this Syndrome according to research I conducted.
Wolfram Syndrome is believed to be caused by a malfunction of the mitochondria and also a malfunction of myelenation.
The mitochondrial malfunction has to do with the wolframin gene and the making of the wolframin protein. The wolframin gene is active cellulary in the body especially in the heart, brain, lungs, inner ear and pancreas. There may be autosomal recessive or dominant or mitochondrial inheritance.
The myelination malfunction may cause an effect similar to multiple sclerosis.
This patient was treated with massage, electrical stimulation, hot pack and chiropractic adjustments for two months. The patient claimed he was not as tired as he was before treatment, had less pain in the neck and back and had an increase in his muscle tone. But, the Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy and Deafness remained about the same.
There is no known treatment for Wolfram Syndrome and the life expectancy of people with DIDMOAD is about 30 years.
During the time I was practicing and administering this practice a patient came in with neck pain, and back pain with muscle weakness. In the process of taking a case history he revealed to me that he was diagnosed with Wolfram Syndrome (DIDMOAD). He was American of Greek ancestry, short for his age, early 20's, had Diabetes Insipidus,Diabetes Mellitus, Optic Atropy and some Deafness, he also had weakness of the kidney's and muscular weakness and constant fatigue.
The primary symptoms of Wolfram Syndrome (DIDMOAD) are Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy and Deafness and various other disorders can be associated. This Syndrome affects the brain (especially the brain stem) and the central nervous system. At the time I was taking care of this gentleman he was only one of 167 people in the world that were known to have this Syndrome according to research I conducted.
Wolfram Syndrome is believed to be caused by a malfunction of the mitochondria and also a malfunction of myelenation.
The mitochondrial malfunction has to do with the wolframin gene and the making of the wolframin protein. The wolframin gene is active cellulary in the body especially in the heart, brain, lungs, inner ear and pancreas. There may be autosomal recessive or dominant or mitochondrial inheritance.
The myelination malfunction may cause an effect similar to multiple sclerosis.
This patient was treated with massage, electrical stimulation, hot pack and chiropractic adjustments for two months. The patient claimed he was not as tired as he was before treatment, had less pain in the neck and back and had an increase in his muscle tone. But, the Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy and Deafness remained about the same.
There is no known treatment for Wolfram Syndrome and the life expectancy of people with DIDMOAD is about 30 years.
Labels: WOLFRAM SYNDROME
posted by comprehensive | 8:29 PM
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